The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway

Death-associated protein kinase (DAPK) is a calmodulin-regulated serine/threonine kinase and possesses apoptotic and tumor-suppressive functions. However, it is unclear whether DAPK elicits apoptosis-independent activity to suppress tumor progression. We show that DAPK inhibits random migration by r...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuo, Jean-Cheng, Wang, Won-Jing, Yao, Chung-Chen, Wu, Pei-Rung, Chen, Ruey-Hwa
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063680/
https://www.ncbi.nlm.nih.gov/pubmed/16476779
http://dx.doi.org/10.1083/jcb.200505138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063680/
https://www.ncbi.nlm.nih.gov/pubmed/16476779
http://dx.doi.org/10.1083/jcb.200505138

Ejemplares similares