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The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway

Death-associated protein kinase (DAPK) is a calmodulin-regulated serine/threonine kinase and possesses apoptotic and tumor-suppressive functions. However, it is unclear whether DAPK elicits apoptosis-independent activity to suppress tumor progression. We show that DAPK inhibits random migration by r...

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Detalles Bibliográficos
Autores principales:	Kuo, Jean-Cheng, Wang, Won-Jing, Yao, Chung-Chen, Wu, Pei-Rung, Chen, Ruey-Hwa
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063680/ https://www.ncbi.nlm.nih.gov/pubmed/16476779 http://dx.doi.org/10.1083/jcb.200505138

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