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Myelin under construction—teamwork required

Myelinating glial cells synthesize specialized myelin proteins and deposit them in the growing myelin sheath that enwraps axons multiple times. How do axons and myelinating glial cells coordinate this spectacular cell–cell interaction? In this issue, Trajkovic et al. (p. 937) show that neuronal sign...

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Detalles Bibliográficos
Autores principales: Boiko, Tatiana, Winckler, Bettina
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063723/
https://www.ncbi.nlm.nih.gov/pubmed/16533942
http://dx.doi.org/10.1083/jcb.200602101
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author Boiko, Tatiana
Winckler, Bettina
author_facet Boiko, Tatiana
Winckler, Bettina
author_sort Boiko, Tatiana
collection PubMed
description Myelinating glial cells synthesize specialized myelin proteins and deposit them in the growing myelin sheath that enwraps axons multiple times. How do axons and myelinating glial cells coordinate this spectacular cell–cell interaction? In this issue, Trajkovic et al. (p. 937) show that neuronal signaling regulates cell surface expression of the myelin proteolipid protein in cultured oligodendrocytes in unexpected ways that may also contribute to myelination in situ.
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spelling pubmed-20637232007-11-29 Myelin under construction—teamwork required Boiko, Tatiana Winckler, Bettina J Cell Biol Reviews Myelinating glial cells synthesize specialized myelin proteins and deposit them in the growing myelin sheath that enwraps axons multiple times. How do axons and myelinating glial cells coordinate this spectacular cell–cell interaction? In this issue, Trajkovic et al. (p. 937) show that neuronal signaling regulates cell surface expression of the myelin proteolipid protein in cultured oligodendrocytes in unexpected ways that may also contribute to myelination in situ. The Rockefeller University Press 2006-03-13 /pmc/articles/PMC2063723/ /pubmed/16533942 http://dx.doi.org/10.1083/jcb.200602101 Text en Copyright © 2006, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Reviews
Boiko, Tatiana
Winckler, Bettina
Myelin under construction—teamwork required
title Myelin under construction—teamwork required
title_full Myelin under construction—teamwork required
title_fullStr Myelin under construction—teamwork required
title_full_unstemmed Myelin under construction—teamwork required
title_short Myelin under construction—teamwork required
title_sort myelin under construction—teamwork required
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063723/
https://www.ncbi.nlm.nih.gov/pubmed/16533942
http://dx.doi.org/10.1083/jcb.200602101
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