The Drosophila melanogaster Apaf-1 homologue ARK is required for most, but not all, programmed cell death

The Apaf-1 protein is essential for cytochrome c–mediated caspase-9 activation in the intrinsic mammalian pathway of apoptosis. Although Apaf-1 is the only known mammalian homologue of the Caenorhabditis elegans CED-4 protein, the deficiency of apaf-1 in cells or in mice results in a limited cell su...

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Detalles Bibliográficos
Autores principales: Mills, Kathryn, Daish, Tasman, Harvey, Kieran F., Pfleger, Cathie M., Hariharan, Iswar K., Kumar, Sharad
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063725/
https://www.ncbi.nlm.nih.gov/pubmed/16533943
http://dx.doi.org/10.1083/jcb.200512126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063725/
https://www.ncbi.nlm.nih.gov/pubmed/16533943
http://dx.doi.org/10.1083/jcb.200512126

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