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Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression

Separase is a protease whose liberation from its inhibitory chaperone Securin triggers sister chromatid disjunction at anaphase onset in yeast by cleaving cohesin's kleisin subunit. We have created conditional knockout alleles of the mouse Separase and Securin genes. Deletion of both copies of...

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Detalles Bibliográficos
Autores principales:	Wirth, Karin G., Wutz, Gordana, Kudo, Nobuaki R., Desdouets, Chantal, Zetterberg, Anders, Taghybeeglu, Shahryar, Seznec, Janina, Ducos, Germain M., Ricci, Romeo, Firnberg, Nicole, Peters, Jan-Michael, Nasmyth, Kim
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063729/ https://www.ncbi.nlm.nih.gov/pubmed/16533945 http://dx.doi.org/10.1083/jcb.200506119

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