Controversy fuels trafficking of GPI-anchored proteins

The model that glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) take a direct transport route to the apical membrane of epithelial cells has recently been challenged. In this issue, Paladino et al. (p. 1023) and Hua et al. (p. 1035) show that the original view nevertheless holds. This...

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Detalles Bibliográficos
Autores principales: Schuck, Sebastian, Simons, Kai
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063753/
https://www.ncbi.nlm.nih.gov/pubmed/16567497
http://dx.doi.org/10.1083/jcb.200603015
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author Schuck, Sebastian
Simons, Kai
author_facet Schuck, Sebastian
Simons, Kai
author_sort Schuck, Sebastian
collection PubMed
description The model that glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) take a direct transport route to the apical membrane of epithelial cells has recently been challenged. In this issue, Paladino et al. (p. 1023) and Hua et al. (p. 1035) show that the original view nevertheless holds. This closes a chapter in the winding story of GPI-AP trafficking but opens another phase, as the controversy has stimulated the development of new methodology.
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spelling pubmed-20637532007-11-29 Controversy fuels trafficking of GPI-anchored proteins Schuck, Sebastian Simons, Kai J Cell Biol Reviews The model that glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) take a direct transport route to the apical membrane of epithelial cells has recently been challenged. In this issue, Paladino et al. (p. 1023) and Hua et al. (p. 1035) show that the original view nevertheless holds. This closes a chapter in the winding story of GPI-AP trafficking but opens another phase, as the controversy has stimulated the development of new methodology. The Rockefeller University Press 2006-03-27 /pmc/articles/PMC2063753/ /pubmed/16567497 http://dx.doi.org/10.1083/jcb.200603015 Text en Copyright © 2006, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Reviews
Schuck, Sebastian
Simons, Kai
Controversy fuels trafficking of GPI-anchored proteins
title Controversy fuels trafficking of GPI-anchored proteins
title_full Controversy fuels trafficking of GPI-anchored proteins
title_fullStr Controversy fuels trafficking of GPI-anchored proteins
title_full_unstemmed Controversy fuels trafficking of GPI-anchored proteins
title_short Controversy fuels trafficking of GPI-anchored proteins
title_sort controversy fuels trafficking of gpi-anchored proteins
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063753/
https://www.ncbi.nlm.nih.gov/pubmed/16567497
http://dx.doi.org/10.1083/jcb.200603015
work_keys_str_mv AT schucksebastian controversyfuelstraffickingofgpianchoredproteins
AT simonskai controversyfuelstraffickingofgpianchoredproteins

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