Lamina-associated polypeptide 2α regulates cell cycle progression and differentiation via the retinoblastoma–E2F pathway

Lamina-associated polypeptide (LAP) 2α is a nonmembrane-bound LAP2 isoform that forms complexes with nucleoplasmic A-type lamins. In this study, we show that the overexpression of LAP2α in fibroblasts reduced proliferation and delayed entry into the cell cycle from a G0 arrest. In contrast, stable d...

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Detalles Bibliográficos
Autores principales: Dorner, Daniela, Vlcek, Sylvia, Foeger, Nicole, Gajewski, Andreas, Makolm, Christian, Gotzmann, Josef, Hutchison, Christopher J., Foisner, Roland
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063793/
https://www.ncbi.nlm.nih.gov/pubmed/16606692
http://dx.doi.org/10.1083/jcb.200511149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063793/
https://www.ncbi.nlm.nih.gov/pubmed/16606692
http://dx.doi.org/10.1083/jcb.200511149

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