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Internalization is required for proper Wingless signaling in Drosophila melanogaster

The Wnt–Wingless (Wg) pathway regulates development through precisely controlled signaling. In this study, we show that intracellular trafficking regulates Wg signaling levels. In Drosophila melanogaster cells stimulated with Wg media, dynamin or Rab5 knockdown causes reduced Super8XTOPflash activit...

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Detalles Bibliográficos
Autores principales:	Seto, Elaine S., Bellen, Hugo J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063794/ https://www.ncbi.nlm.nih.gov/pubmed/16606693 http://dx.doi.org/10.1083/jcb.200510123

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