Cargando…
Formation of a WIP-, WASp-, actin-, and myosin IIA–containing multiprotein complex in activated NK cells and its alteration by KIR inhibitory signaling
The tumor natural killer (NK) cell line YTS was used to examine the cytoskeletal rearrangements required for cytolysis. A multiprotein complex weighing ∼1.3 mD and consisting of WASp-interacting protein (WIP), Wiskott-Aldrich syndrome protein (WASp), actin, and myosin IIA that formed during NK cell...
Autores principales: | Krzewski, Konrad, Chen, Xi, Orange, Jordan S., Strominger, Jack L. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063796/ https://www.ncbi.nlm.nih.gov/pubmed/16606694 http://dx.doi.org/10.1083/jcb.200509076 |
Ejemplares similares
-
Myosin IIA is required for cytolytic granule exocytosis in human NK cells
por: Andzelm, Milena M., et al.
Publicado: (2007) -
WIP Provides an Essential Link between Nck and N-WASP during Arp2/3-Dependent Actin Polymerization
por: Donnelly, Sara K., et al.
Publicado: (2013) -
WIP Remodeling Actin behind the Scenes: How WIP Reshapes Immune and Other Functions
por: Noy, Elad, et al.
Publicado: (2012) -
WIP Regulates the Stability and Localization of WASP to Podosomes in Migrating Dendritic Cells
por: Chou, Hsiu-Chuan, et al.
Publicado: (2006) -
Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages
por: Vijayakumar, Vineetha, et al.
Publicado: (2015)