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Structural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template model
The inheritance of a normal assortment of chromosomes during each cell division relies on a cell-cycle surveillance system called the mitotic spindle checkpoint. The existence of sister chromatids that do not achieve proper bipolar attachment to the mitotic spindle in a cell activates this checkpoin...
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063805/ https://www.ncbi.nlm.nih.gov/pubmed/16636141 http://dx.doi.org/10.1083/jcb.200601172 |