A kinase-deficient TrkC receptor isoform activates Arf6–Rac1 signaling through the scaffold protein tamalin

Neurotrophins play an essential role in mammalian development. Most of their functions have been attributed to activation of the kinase-active Trk receptors and the p75 neurotrophin receptor. Truncated Trk receptor isoforms lacking the kinase domain are abundantly expressed during development and in...

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Detalles Bibliográficos
Autores principales: Esteban, Pedro F., Yoon, Hye-Young, Becker, Jodi, Dorsey, Susan G., Caprari, Paola, Palko, Mary Ellen, Coppola, Vincenzo, Saragovi, H. Uri, Randazzo, Paul A., Tessarollo, Lino
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063819/
https://www.ncbi.nlm.nih.gov/pubmed/16636148
http://dx.doi.org/10.1083/jcb.200512013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063819/
https://www.ncbi.nlm.nih.gov/pubmed/16636148
http://dx.doi.org/10.1083/jcb.200512013

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