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The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors
Understanding the mechanisms controlling cancer cell invasion and metastasis constitutes a fundamental step in setting new strategies for diagnosis, prognosis, and therapy of metastatic cancers. LIM kinase1 (LIMK1) is a member of a novel class of serine–threonine protein kinases. Cofilin, a LIMK1 su...
Autores principales: | Wang, Weigang, Mouneimne, Ghassan, Sidani, Mazen, Wyckoff, Jeffrey, Chen, Xiaoming, Makris, Anastasia, Goswami, Sumanta, Bresnick, Anne R., Condeelis, John S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063840/ https://www.ncbi.nlm.nih.gov/pubmed/16651380 http://dx.doi.org/10.1083/jcb.200510115 |
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