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Drosophila melanogaster auxilin regulates the internalization of Delta to control activity of the Notch signaling pathway
We have isolated mutations in the Drosophila melanogaster homologue of auxilin, a J-domain–containing protein known to cooperate with Hsc70 in the disassembly of clathrin coats from clathrin-coated vesicles in vitro. Consistent with this biochemical role, animals with reduced auxilin function exhibi...
Autores principales: | Hagedorn, Elliott J., Bayraktar, Jennifer L., Kandachar, Vasundhara R., Bai, Ting, Englert, Dane M., Chang, Henry C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063844/ https://www.ncbi.nlm.nih.gov/pubmed/16682530 http://dx.doi.org/10.1083/jcb.200602054 |
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