Cargando…
Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate
The activity of the p53 gene product is regulated by a plethora of posttranslational modifications. An open question is whether such posttranslational changes act redundantly or dependently upon one another. We show that a functional interference between specific acetylated and phosphorylated residu...
Autores principales: | Knights, Chad D., Catania, Jason, Giovanni, Simone Di, Muratoglu, Selen, Perez, Ricardo, Swartzbeck, Amber, Quong, Andrew A., Zhang, Xiaojing, Beerman, Terry, Pestell, Richard G., Avantaggiati, Maria Laura |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063863/ https://www.ncbi.nlm.nih.gov/pubmed/16717128 http://dx.doi.org/10.1083/jcb.200512059 |
Ejemplares similares
-
Acetylation of the Cell-Fate Factor Dachshund Determines p53 Binding and Signaling Modules in Breast Cancer
por: Chen, Ke, et al.
Publicado: (2013) -
Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity
por: Schlottmann, Silke, et al.
Publicado: (2012) -
The SLC25A1-p53 mutant crosstalk
por: Albanese, Chris, et al.
Publicado: (2015) -
53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms
por: Cuella-Martin, Raquel, et al.
Publicado: (2016) -
Macrophage LRP1 Suppresses Neo-Intima Formation during Vascular Remodeling by Modulating the TGF-β Signaling Pathway
por: Muratoglu, Selen Catania, et al.
Publicado: (2011)