“HURP on” we're off to the kinetochore!

RanGTP has a central role in spindle assembly, but the Ran-regulated factors required to initiate spindle bipolarity and stabilize MT growth toward the chromosomes remain unknown. However, three recent papers (Koffa et al., 2006; Sillje et al., 2006; Wong and Fang, 2006) have identified a single fac...

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Detalles Bibliográficos
Autor principal: Wilde, Andrew
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063907/
https://www.ncbi.nlm.nih.gov/pubmed/16785318
http://dx.doi.org/10.1083/jcb.200605150
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author Wilde, Andrew
author_facet Wilde, Andrew
author_sort Wilde, Andrew
collection PubMed
description RanGTP has a central role in spindle assembly, but the Ran-regulated factors required to initiate spindle bipolarity and stabilize MT growth toward the chromosomes remain unknown. However, three recent papers (Koffa et al., 2006; Sillje et al., 2006; Wong and Fang, 2006) have identified a single factor, HURP, that may encompass both of these properties.
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spelling pubmed-20639072007-11-29 “HURP on” we're off to the kinetochore! Wilde, Andrew J Cell Biol Reviews RanGTP has a central role in spindle assembly, but the Ran-regulated factors required to initiate spindle bipolarity and stabilize MT growth toward the chromosomes remain unknown. However, three recent papers (Koffa et al., 2006; Sillje et al., 2006; Wong and Fang, 2006) have identified a single factor, HURP, that may encompass both of these properties. The Rockefeller University Press 2006-06-19 /pmc/articles/PMC2063907/ /pubmed/16785318 http://dx.doi.org/10.1083/jcb.200605150 Text en Copyright © 2006, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Reviews
Wilde, Andrew
“HURP on” we're off to the kinetochore!
title “HURP on” we're off to the kinetochore!
title_full “HURP on” we're off to the kinetochore!
title_fullStr “HURP on” we're off to the kinetochore!
title_full_unstemmed “HURP on” we're off to the kinetochore!
title_short “HURP on” we're off to the kinetochore!
title_sort “hurp on” we're off to the kinetochore!
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063907/
https://www.ncbi.nlm.nih.gov/pubmed/16785318
http://dx.doi.org/10.1083/jcb.200605150
work_keys_str_mv AT wildeandrew hurponwereofftothekinetochore

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