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HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture
Through a functional genomic screen for mitotic regulators, we identified hepatoma up-regulated protein (HURP) as a protein that is required for chromosome congression and alignment. In HURP-depleted cells, the persistence of unaligned chromosomes and the reduction of tension across sister kinetocho...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063914/ https://www.ncbi.nlm.nih.gov/pubmed/16769820 http://dx.doi.org/10.1083/jcb.200511132 |