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Nebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscle

Nebulin is a giant modular sarcomeric protein that has been proposed to play critical roles in myofibrillogenesis, thin filament length regulation, and muscle contraction. To investigate the functional role of nebulin in vivo, we generated nebulin-deficient mice by using a Cre knock-in strategy. Lin...

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Detalles Bibliográficos
Autores principales:	Bang, Marie-Louise, Li, Xiaodong, Littlefield, Ryan, Bremner, Shannon, Thor, Andrea, Knowlton, Kirk U., Lieber, Richard L., Chen, Ju
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063916/ https://www.ncbi.nlm.nih.gov/pubmed/16769824 http://dx.doi.org/10.1083/jcb.200603119

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