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Palmitoylation-dependent protein sorting

S-palmitoylation is a posttranslational modification that regulates membrane–protein interactions. However, palmitate is more than just a hydrophobic membrane anchor, as many different types of protein are palmitoylated, including transmembrane proteins. Indeed, there is now compelling evidence that...

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Detalles Bibliográficos
Autores principales: Greaves, Jennifer, Chamberlain, Luke H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063950/
https://www.ncbi.nlm.nih.gov/pubmed/17242068
http://dx.doi.org/10.1083/jcb.200610151
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author Greaves, Jennifer
Chamberlain, Luke H.
author_facet Greaves, Jennifer
Chamberlain, Luke H.
author_sort Greaves, Jennifer
collection PubMed
description S-palmitoylation is a posttranslational modification that regulates membrane–protein interactions. However, palmitate is more than just a hydrophobic membrane anchor, as many different types of protein are palmitoylated, including transmembrane proteins. Indeed, there is now compelling evidence that palmitoylation plays a key role in regulating various aspects of protein sorting within the cell.
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spelling pubmed-20639502007-11-29 Palmitoylation-dependent protein sorting Greaves, Jennifer Chamberlain, Luke H. J Cell Biol Reviews S-palmitoylation is a posttranslational modification that regulates membrane–protein interactions. However, palmitate is more than just a hydrophobic membrane anchor, as many different types of protein are palmitoylated, including transmembrane proteins. Indeed, there is now compelling evidence that palmitoylation plays a key role in regulating various aspects of protein sorting within the cell. The Rockefeller University Press 2007-01-29 /pmc/articles/PMC2063950/ /pubmed/17242068 http://dx.doi.org/10.1083/jcb.200610151 Text en Copyright © 2007, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Reviews
Greaves, Jennifer
Chamberlain, Luke H.
Palmitoylation-dependent protein sorting
title Palmitoylation-dependent protein sorting
title_full Palmitoylation-dependent protein sorting
title_fullStr Palmitoylation-dependent protein sorting
title_full_unstemmed Palmitoylation-dependent protein sorting
title_short Palmitoylation-dependent protein sorting
title_sort palmitoylation-dependent protein sorting
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063950/
https://www.ncbi.nlm.nih.gov/pubmed/17242068
http://dx.doi.org/10.1083/jcb.200610151
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