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FAK is required for axonal sorting by Schwann cells

Signaling by laminins and axonal neuregulin has been implicated in regulating axon sorting by myelin-forming Schwann cells. However, the signal transduction mechanisms are unknown. Focal adhesion kinase (FAK) has been linked to α6β1 integrin and ErbB receptor signaling, and we show that myelination...

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Detalles Bibliográficos
Autores principales: Grove, Matthew, Komiyama, Noboru H., Nave, Klaus-Armin, Grant, Seth G., Sherman, Diane L., Brophy, Peter J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063954/
https://www.ncbi.nlm.nih.gov/pubmed/17242067
http://dx.doi.org/10.1083/jcb.200609021