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SecY alterations that impair membrane protein folding and generate a membrane stress

We report on a class of Escherichia coli SecY mutants that impair membrane protein folding. The mutants also up-regulate the Cpx/σ(E) stress response pathways. Similar stress induction was also observed in response to a YidC defect in membrane protein biogenesis but not in response to the signal rec...

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Detalles Bibliográficos
Autores principales: Shimohata, Nobuyuki, Nagamori, Shushi, Akiyama, Yoshinori, Kaback, H. Ronald, Ito, Koreaki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063957/
https://www.ncbi.nlm.nih.gov/pubmed/17242069
http://dx.doi.org/10.1083/jcb.200611121