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SecY alterations that impair membrane protein folding and generate a membrane stress
We report on a class of Escherichia coli SecY mutants that impair membrane protein folding. The mutants also up-regulate the Cpx/σ(E) stress response pathways. Similar stress induction was also observed in response to a YidC defect in membrane protein biogenesis but not in response to the signal rec...
Autores principales: | Shimohata, Nobuyuki, Nagamori, Shushi, Akiyama, Yoshinori, Kaback, H. Ronald, Ito, Koreaki |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063957/ https://www.ncbi.nlm.nih.gov/pubmed/17242069 http://dx.doi.org/10.1083/jcb.200611121 |
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