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Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa

To identify the mechanisms of ultraviolet radiation (UVR)–induced cell death, for which the tumor suppressor p53 is essential, we have analyzed mouse embryonic fibroblasts (MEFs) and keratinocytes in mouse skin that have specific apoptotic pathways blocked genetically. Blocking the death receptor pa...

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Detalles Bibliográficos
Autores principales:	Naik, Edwina, Michalak, Ewa M., Villunger, Andreas, Adams, Jerry M., Strasser, Andreas
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063977/ https://www.ncbi.nlm.nih.gov/pubmed/17283183 http://dx.doi.org/10.1083/jcb.200608070

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