Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells

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We have used isoform-specific RNA interference knockdowns to investigate the roles of myosin IIA (MIIA) and MIIB in the component processes that drive cell migration. Both isoforms reside outside of protrusions and act at a distance to regulate cell protrusion, signaling, and maturation of nascent a...

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Detalles Bibliográficos
Autores principales: Vicente-Manzanares, Miguel, Zareno, Jessica, Whitmore, Leanna, Choi, Colin K., Horwitz, Alan F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064016/
https://www.ncbi.nlm.nih.gov/pubmed/17312025
http://dx.doi.org/10.1083/jcb.200612043

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