RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females

RAD51C is a member of the RecA/RAD51 protein family, which is known to play an important role in DNA repair by homologous recombination. In mice, it is essential for viability. Therefore, we have generated a hypomorphic allele of Rad51c in addition to a null allele. A subset of mice expressing the h...

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Detalles Bibliográficos
Autores principales: Kuznetsov, Sergey, Pellegrini, Manuela, Shuda, Kristy, Fernandez-Capetillo, Oscar, Liu, Yilun, Martin, Betty K., Burkett, Sandra, Southon, Eileen, Pati, Debananda, Tessarollo, Lino, West, Stephen C., Donovan, Peter J., Nussenzweig, Andre, Sharan, Shyam K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064017/
https://www.ncbi.nlm.nih.gov/pubmed/17312021
http://dx.doi.org/10.1083/jcb.200608130

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