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Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux
Endoplasmic reticulum (ER) homeostasis requires transfer and subsequent processing of the glycan Glc(3)Man(9)GlcNAc(2) (G(3)M(9)Gn(2)) from the lipid-linked oligosaccharide (LLO) glucose(3)mannose(9)N-acetylglucosamine(2)-P-P-dolichol (G(3)M(9)Gn(2)-P-P-Dol) to asparaginyl residues of nascent glycop...
Autores principales: | Shang, Jie, Gao, Ningguo, Kaufman, Randal J., Ron, David, Harding, Heather P., Lehrman, Mark A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064019/ https://www.ncbi.nlm.nih.gov/pubmed/17325203 http://dx.doi.org/10.1083/jcb.200607007 |
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