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PPARγ1 attenuates cytosol to membrane translocation of PKCα to desensitize monocytes/macrophages

Recently, we provided evidence that PKCα depletion in monocytes/macrophages contributes to cellular desensitization during sepsis. We demonstrate that peroxisome proliferator–activated receptor γ (PPARγ) agonists dose dependently block PKCα depletion in response to the diacylglycerol homologue PMA i...

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Detalles Bibliográficos
Autores principales:	von Knethen, Andreas, Soller, Mathias, Tzieply, Nico, Weigert, Andreas, Johann, Axel M., Jennewein, Carla, Köhl, Roman, Brüne, Bernhard
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064025/ https://www.ncbi.nlm.nih.gov/pubmed/17325208 http://dx.doi.org/10.1083/jcb.200605038

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