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A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle

Mutations in human survival motor neurons 1 (SMN1) cause spinal muscular atrophy (SMA) and are associated with defects in assembly of small nuclear ribonucleoproteins (snRNPs) in vitro. However, the etiological link between snRNPs and SMA is unclear. We have developed a Drosophila melanogaster syste...

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Detalles Bibliográficos
Autores principales:	Rajendra, T.K., Gonsalvez, Graydon B., Walker, Michael P., Shpargel, Karl B., Salz, Helen K., Matera, A. Gregory
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064057/ https://www.ncbi.nlm.nih.gov/pubmed/17353360 http://dx.doi.org/10.1083/jcb.200610053

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