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Rap1 controls cell adhesion and cell motility through the regulation of myosin II
We have investigated the role of Rap1 in controlling chemotaxis and cell adhesion in Dictyostelium discoideum. Rap1 is activated rapidly in response to chemoattractant stimulation, and activated Rap1 is preferentially found at the leading edge of chemotaxing cells. Cells expressing constitutively ac...
Autores principales: | Jeon, Taeck J., Lee, Dai-Jen, Merlot, Sylvain, Weeks, Gerald, Firtel, Richard A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064086/ https://www.ncbi.nlm.nih.gov/pubmed/17371831 http://dx.doi.org/10.1083/jcb.200607072 |
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