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Phosphorylation and regulation of a G protein–coupled receptor by protein kinase CK2

We demonstrate a role for protein kinase casein kinase 2 (CK2) in the phosphorylation and regulation of the M(3)-muscarinic receptor in transfected cells and cerebellar granule neurons. On agonist occupation, specific subsets of receptor phosphoacceptor sites (which include the SASSDEED motif in the...

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Detalles Bibliográficos
Autores principales: Torrecilla, Ignacio, Spragg, Elizabeth J., Poulin, Benoit, McWilliams, Phillip J., Mistry, Sharad C., Blaukat, Andree, Tobin, Andrew B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064117/
https://www.ncbi.nlm.nih.gov/pubmed/17403928
http://dx.doi.org/10.1083/jcb.200610018