Cargando…

Transforming growth factor-β employs HMGA2 to elicit epithelial–mesenchymal transition

Epithelial–mesenchymal transition (EMT) occurs during embryogenesis, carcinoma invasiveness, and metastasis and can be elicited by transforming growth factor-β (TGF-β) signaling via intracellular Smad transducers. The molecular mechanisms that control the onset of EMT remain largely unexplored. Tran...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thuault, Sylvie, Valcourt, Ulrich, Petersen, Maj, Manfioletti, Guidalberto, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064178/ https://www.ncbi.nlm.nih.gov/pubmed/16831886 http://dx.doi.org/10.1083/jcb.200512110

Ejemplares similares

The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition
por: Tan, E-Jean, et al.
Publicado: (2015)

Mechanisms of TGFβ-Induced Epithelial–Mesenchymal Transition
por: Moustakas, Aristidis, et al.
Publicado: (2016)

Epithelial–Mesenchymal Transition (EMT)
por: Manfioletti, Guidalberto, et al.
Publicado: (2023)

Epithelial–Mesenchymal Transition (EMT) 2021
por: Manfioletti, Guidalberto, et al.
Publicado: (2022)

HMGA2 Antisense Long Non-coding RNAs as New Players in the Regulation of HMGA2 Expression and Pancreatic Cancer Promotion
por: Ros, Gloria, et al.
Publicado: (2020)

Notch signaling is necessary for epithelial growth arrest by TGF-β
por: Niimi, Hideki, et al.
Publicado: (2007)

Epithelial-Mesenchymal Transition and Metastasis under the Control of Transforming Growth Factor β
por: Tsubakihara, Yutaro, et al.
Publicado: (2018)

A novel HMGA1-CCNE2-YAP axis regulates breast cancer aggressiveness
por: Pegoraro, Silvia, et al.
Publicado: (2015)

Extracellular Vesicles and Transforming Growth Factor β Signaling in Cancer
por: Rodrigues-Junior, Dorival Mendes, et al.
Publicado: (2022)

The Epithelial–Mesenchymal Transition at the Crossroads between Metabolism and Tumor Progression
por: Fedele, Monica, et al.
Publicado: (2022)

The second AT-hook of the architectural transcription factor HMGA2 is determinant for nuclear localization and function
por: Cattaruzzi, Giacomo, et al.
Publicado: (2007)

Transforming growth factor β (TGFβ) induces NUAK kinase expression to fine-tune its signaling output
por: Kolliopoulos, Constantinos, et al.
Publicado: (2019)

Transcriptional Regulation of Glucose Metabolism: The Emerging Role of the HMGA1 Chromatin Factor
por: Chiefari, Eusebio, et al.
Publicado: (2018)

A novel mechanism of post-translational modulation of HMGA functions by the histone chaperone nucleophosmin
por: Arnoldo, Laura, et al.
Publicado: (2015)

Negative Regulation of TGFβ Signaling by the Kinase LKB1 and the Scaffolding Protein LIP1
por: Morén, Anita, et al.
Publicado: (2011)

Genome–wide binding of transcription factor ZEB1 in triple‐negative breast cancer cells
por: Maturi, Varun, et al.
Publicado: (2018)

HMGA1 Regulates the Expression of Replication-Dependent Histone Genes and Cell-Cycle in Breast Cancer Cells
por: Petrosino, Sara, et al.
Publicado: (2022)

Transforming Growth Factor β Promotes Complexes between Smad Proteins and the CCCTC-binding Factor on the H19 Imprinting Control Region Chromatin
por: Bergström, Rosita, et al.
Publicado: (2010)

HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness
por: Pegoraro, Silvia, et al.
Publicado: (2013)

HMGA1 regulates the Plasminogen activation system in the secretome of breast cancer cells
por: Resmini, Giulia, et al.
Publicado: (2017)

Epithelial–mesenchymal transition in cancer
por: Moustakas, Aristidis, et al.
Publicado: (2017)

Selection of Natural Compounds with HMGA-Interfering Activities and Cancer Cell Cytotoxicity
por: Mori, Mattia, et al.
Publicado: (2023)

High Mobility Group A (HMGA): Chromatin Nodes Controlled by a Knotty miRNA Network
por: Sgarra, Riccardo, et al.
Publicado: (2020)

HMGA1 positively regulates the microtubule-destabilizing protein stathmin promoting motility in TNBC cells and decreasing tumour sensitivity to paclitaxel
por: Sgubin, Michela, et al.
Publicado: (2022)

Genomewide binding of transcription factor Snail1 in triple‐negative breast cancer cells
por: Maturi, Varun, et al.
Publicado: (2018)

Loss of SNAI1 induces cellular plasticity in invasive triple-negative breast cancer cells
por: Tsirigoti, Chrysoula, et al.
Publicado: (2022)

HMGA1 Modulates Gene Transcription Sustaining a Tumor Signalling Pathway Acting on the Epigenetic Status of Triple-Negative Breast Cancer Cells
por: Penzo, Carlotta, et al.
Publicado: (2019)

The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor β signaling
por: Papoutsoglou, Panagiotis, et al.
Publicado: (2021)

HMGA1 is a novel downstream nuclear target of the insulin receptor signaling pathway
por: Chiefari, Eusebio, et al.
Publicado: (2012)

TGFβ induces SIK to negatively regulate type I receptor kinase signaling
por: Kowanetz, Marcin, et al.
Publicado: (2008)

Emergence, development and diversification of the TGF-β signalling pathway within the animal kingdom
por: Huminiecki, Lukasz, et al.
Publicado: (2009)

TGFβ selects for pro‐stemness over pro‐invasive phenotypes during cancer cell epithelial–mesenchymal transition
por: Tsubakihara, Yutaro, et al.
Publicado: (2022)

Proneural-Mesenchymal Transition: Phenotypic Plasticity to Acquire Multitherapy Resistance in Glioblastoma
por: Fedele, Monica, et al.
Publicado: (2019)

HMGA1 promotes breast cancer angiogenesis supporting the stability, nuclear localization and transcriptional activity of FOXM1
por: Zanin, Rossella, et al.
Publicado: (2019)

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation
por: Carthy, Jon M., et al.
Publicado: (2016)

Editorial: Hormone Receptors and Breast Cancer
por: Brunetti, Antonio, et al.
Publicado: (2019)

Snail mediates crosstalk between TGFβ and LXRα in hepatocellular carcinoma
por: Bellomo, Claudia, et al.
Publicado: (2017)

LXRα limits TGFβ-dependent hepatocellular carcinoma associated fibroblast differentiation
por: Morén, Anita, et al.
Publicado: (2019)

Translating Proteomic Into Functional Data: An High Mobility Group A1 (HMGA1) Proteomic Signature Has Prognostic Value in Breast Cancer
por: Maurizio, Elisa, et al.
Publicado: (2016)

The High Mobility Group A1 (HMGA1) Chromatin Architectural Factor Modulates Nuclear Stiffness in Breast Cancer Cells
por: Senigagliesi, Beatrice, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_geep6h4mh7rfedbj27i7s5g8lr