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LMP4 regulates Tbx5 protein subcellular localization and activity

The limb- and heart-specific Tbx5 transcription factor coexpresses with and directly binds to the novel PDZ-LIM domain protein, LMP4. LMP4 is distributed in the cytoplasm associated with the actin cytoskeleton. In the presence of LMP4, Tbx5 shuttles dynamically between the nucleus and cytoplasm and,...

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Detalles Bibliográficos
Autores principales: Camarata, Troy, Bimber, Benjamin, Kulisz, Andre, Chew, Teng-Leong, Yeung, Jennifer, Simon, Hans-Georg
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064230/
https://www.ncbi.nlm.nih.gov/pubmed/16880269
http://dx.doi.org/10.1083/jcb.200511109

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