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Requirement of dendritic Akt degradation by the ubiquitin–proteasome system for neuronal polarity
Asymmetric distributions of activities of the protein kinases Akt and glycogen synthase kinase 3β (GSK-3β) are critical for the formation of neuronal polarity. However, the mechanisms underlying polarized regulation of this pathway remain unclear. In this study, we report that the instability of Akt...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064237/ https://www.ncbi.nlm.nih.gov/pubmed/16864652 http://dx.doi.org/10.1083/jcb.200511028 |