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Transport of PIP(3) by GAKIN, a kinesin-3 family protein, regulates neuronal cell polarity

Phosphatidylinositol-(3,4,5)-trisphosphate (PIP(3)), a product of phosphatidylinositol 3-kinase, is an important second messenger implicated in signal transduction and membrane transport. In hippocampal neurons, the accumulation of PIP(3) at the tip of neurite initiates the axon specification and ne...

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Detalles Bibliográficos
Autores principales:	Horiguchi, Kaori, Hanada, Toshihiko, Fukui, Yasuhisa, Chishti, Athar H.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064238/ https://www.ncbi.nlm.nih.gov/pubmed/16864656 http://dx.doi.org/10.1083/jcb.200604031

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