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Perturbing integrin function inhibits microtubule growth from centrosomes, spindle assembly, and cytokinesis
In many mammalian cell types, integrin-mediated cell-matrix adhesion is required for the G1–S transition of the cell cycle. As cells approach mitosis, a dramatic remodeling of their cytoskeleton accompanies dynamic changes in matrix adhesion, suggesting a mechanistic link. However, the role of integ...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064255/ https://www.ncbi.nlm.nih.gov/pubmed/16908668 http://dx.doi.org/10.1083/jcb.200603069 |