ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages

The mammalian ATP-binding cassette transporters A1 and A7 (ABCA1 and -A7) show sequence similarity to CED-7, a Caenorhabditis elegans gene that mediates the clearance of apoptotic cells. Using RNA interference or gene targeting, we show that knock down of macrophage ABCA7 but not -A1 results in defe...

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Detalles Bibliográficos
Autores principales: Jehle, Andreas W., Gardai, Shyra J., Li, Suzhao, Linsel-Nitschke, Patrick, Morimoto, Konosuke, Janssen, William J., Vandivier, R. William, Wang, Nan, Greenberg, Steven, Dale, Benjamin M., Qin, Chunbo, Henson, Peter M., Tall, Alan R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064260/
https://www.ncbi.nlm.nih.gov/pubmed/16908670
http://dx.doi.org/10.1083/jcb.200601030

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