Building blood vessels—stem cell models in vascular biology

Spheroids of differentiating embryonic stem cells, denoted embryoid bodies, constitute a high-quality model for vascular development, particularly well suited for loss-of-function analysis of genes required for early embryogenesis. This review examines vasculogenesis and angiogenesis in murine embry...

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Detalles Bibliográficos
Autores principales: Jakobsson, Lars, Kreuger, Johan, Claesson-Welsh, Lena
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064276/
https://www.ncbi.nlm.nih.gov/pubmed/17535968
http://dx.doi.org/10.1083/jcb.200701146
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author Jakobsson, Lars
Kreuger, Johan
Claesson-Welsh, Lena
author_facet Jakobsson, Lars
Kreuger, Johan
Claesson-Welsh, Lena
author_sort Jakobsson, Lars
collection PubMed
description Spheroids of differentiating embryonic stem cells, denoted embryoid bodies, constitute a high-quality model for vascular development, particularly well suited for loss-of-function analysis of genes required for early embryogenesis. This review examines vasculogenesis and angiogenesis in murine embryoid bodies and discusses the promise of stem cell–based models for the study of human vascular development.
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spelling pubmed-20642762007-12-04 Building blood vessels—stem cell models in vascular biology Jakobsson, Lars Kreuger, Johan Claesson-Welsh, Lena J Cell Biol Reviews Spheroids of differentiating embryonic stem cells, denoted embryoid bodies, constitute a high-quality model for vascular development, particularly well suited for loss-of-function analysis of genes required for early embryogenesis. This review examines vasculogenesis and angiogenesis in murine embryoid bodies and discusses the promise of stem cell–based models for the study of human vascular development. The Rockefeller University Press 2007-06-04 /pmc/articles/PMC2064276/ /pubmed/17535968 http://dx.doi.org/10.1083/jcb.200701146 Text en Copyright © 2007, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Reviews
Jakobsson, Lars
Kreuger, Johan
Claesson-Welsh, Lena
Building blood vessels—stem cell models in vascular biology
title Building blood vessels—stem cell models in vascular biology
title_full Building blood vessels—stem cell models in vascular biology
title_fullStr Building blood vessels—stem cell models in vascular biology
title_full_unstemmed Building blood vessels—stem cell models in vascular biology
title_short Building blood vessels—stem cell models in vascular biology
title_sort building blood vessels—stem cell models in vascular biology
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064276/
https://www.ncbi.nlm.nih.gov/pubmed/17535968
http://dx.doi.org/10.1083/jcb.200701146
work_keys_str_mv AT jakobssonlars buildingbloodvesselsstemcellmodelsinvascularbiology
AT kreugerjohan buildingbloodvesselsstemcellmodelsinvascularbiology
AT claessonwelshlena buildingbloodvesselsstemcellmodelsinvascularbiology

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