An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor–stimulated PC12 cells

The local accumulation of phosphatidylinositol (3,4,5) trisphosphate (PIP(3)) and resulting activation of Rac1/Cdc42 play a critical role in nerve growth factor (NGF)–induced neurite outgrowth. To further explore the mechanism, we visualized PIP(3), phosphatidylinositol (3,4) bisphosphate, and Rac1/...

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Detalles Bibliográficos
Autores principales: Aoki, Kazuhiro, Nakamura, Takeshi, Inoue, Takanari, Meyer, Tobias, Matsuda, Michiyuki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064282/
https://www.ncbi.nlm.nih.gov/pubmed/17535963
http://dx.doi.org/10.1083/jcb.200609017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064282/
https://www.ncbi.nlm.nih.gov/pubmed/17535963
http://dx.doi.org/10.1083/jcb.200609017

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