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Contact-dependent inhibition of EGFR signaling by Nf2/Merlin
The neurofibromatosis type 2 (NF2) tumor suppressor, Merlin, is a membrane/cytoskeleton-associated protein that mediates contact-dependent inhibition of proliferation. Here we show that upon cell–cell contact Merlin coordinates the processes of adherens junction stabilization and negative regulation...
Autores principales: | Curto, Marcello, Cole, Banumathi K., Lallemand, Dominique, Liu, Ching-Hui, McClatchey, Andrea I. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064288/ https://www.ncbi.nlm.nih.gov/pubmed/17548515 http://dx.doi.org/10.1083/jcb.200703010 |
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