DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

Neutrophils are highly motile leukocytes, and they play important roles in the innate immune response to invading pathogens. Neutrophil chemotaxis requires Rac activation, yet the Rac activators functioning downstream of chemoattractant receptors remain to be determined. We show that DOCK2, which is...

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Detalles Bibliográficos
Autores principales: Kunisaki, Yuya, Nishikimi, Akihiko, Tanaka, Yoshihiko, Takii, Ryosuke, Noda, Mayuko, Inayoshi, Ayumi, Watanabe, Ken-ichi, Sanematsu, Fumiyuki, Sasazuki, Takehiko, Sasaki, Takehiko, Fukui, Yoshinori
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064308/
https://www.ncbi.nlm.nih.gov/pubmed/16943182
http://dx.doi.org/10.1083/jcb.200602142

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