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The centromere-specific histone variant Cse4p (CENP-A) is essential for functional chromatin architecture at the yeast 2-μm circle partitioning locus and promotes equal plasmid segregation
The centromere protein A homologue Cse4p is required for kinetochore assembly and faithful chromosome segregation in Saccharomyces cerevisiae. It has been regarded as the exquisite hallmark of centromeric chromatin. We demonstrate that Cse4 resides at the partitioning locus STB of the 2-μm plasmid....
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064333/ https://www.ncbi.nlm.nih.gov/pubmed/16966420 http://dx.doi.org/10.1083/jcb.200603042 |