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Genetic analysis of β1 integrin “activation motifs” in mice

Akey feature of integrins is their ability to regulate the affinity for ligands, a process termed integrin activation. The final step in integrin activation is talin binding to the NPXY motif of the integrin β cytoplasmic domains. Talin binding disrupts the salt bridge between the α/β tails, leading...

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Detalles Bibliográficos
Autores principales:	Czuchra, Aleksandra, Meyer, Hannelore, Legate, Kyle R., Brakebusch, Cord, Fässler, Reinhard
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064342/ https://www.ncbi.nlm.nih.gov/pubmed/16954348 http://dx.doi.org/10.1083/jcb.200604060

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