Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore

The eukaryotic spindle assembly checkpoint (SAC) monitors microtubule attachment to kinetochores and prevents anaphase onset until all kinetochores are aligned on the metaphase plate. In higher eukaryotes, cytoplasmic dynein is involved in silencing the SAC by removing the checkpoint proteins Mad2 a...

Descripción completa

Detalles Bibliográficos
Autores principales: Griffis, Eric R., Stuurman, Nico, Vale, Ronald D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064361/
https://www.ncbi.nlm.nih.gov/pubmed/17576797
http://dx.doi.org/10.1083/jcb.200702062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064361/
https://www.ncbi.nlm.nih.gov/pubmed/17576797
http://dx.doi.org/10.1083/jcb.200702062

Ejemplares similares