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C/EBPδ regulates cell cycle and self-renewal of human limbal stem cells
Human limbal stem cells produce transit amplifying progenitors that migrate centripetally to regenerate the corneal epithelium. Coexpression of CCAAT enhancer binding protein δ (C/EBPδ), Bmi1, and ΔNp63α identifies mitotically quiescent limbal stem cells, which generate holoclones in culture. Upon c...
Autores principales: | Barbaro, Vanessa, Testa, Anna, Di Iorio, Enzo, Mavilio, Fulvio, Pellegrini, Graziella, De Luca, Michele |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064364/ https://www.ncbi.nlm.nih.gov/pubmed/17562792 http://dx.doi.org/10.1083/jcb.200703003 |
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