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C/EBPδ regulates cell cycle and self-renewal of human limbal stem cells

Human limbal stem cells produce transit amplifying progenitors that migrate centripetally to regenerate the corneal epithelium. Coexpression of CCAAT enhancer binding protein δ (C/EBPδ), Bmi1, and ΔNp63α identifies mitotically quiescent limbal stem cells, which generate holoclones in culture. Upon c...

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Detalles Bibliográficos
Autores principales: Barbaro, Vanessa, Testa, Anna, Di Iorio, Enzo, Mavilio, Fulvio, Pellegrini, Graziella, De Luca, Michele
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064364/
https://www.ncbi.nlm.nih.gov/pubmed/17562792
http://dx.doi.org/10.1083/jcb.200703003

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