p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway

Clearance of fibrin through proteolytic degradation is a critical step of matrix remodeling that contributes to tissue repair in a variety of pathological conditions, such as stroke, atherosclerosis, and pulmonary disease. However, the molecular mechanisms that regulate fibrin deposition are not kno...

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Detalles Bibliográficos
Autores principales: Sachs, Benjamin D., Baillie, George S., McCall, Julianne R., Passino, Melissa A., Schachtrup, Christian, Wallace, Derek A., Dunlop, Allan J., MacKenzie, Kirsty F., Klussmann, Enno, Lynch, Martin J., Sikorski, Shoana L., Nuriel, Tal, Tsigelny, Igor, Zhang, Jin, Houslay, Miles D., Chao, Moses V., Akassoglou, Katerina
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064370/
https://www.ncbi.nlm.nih.gov/pubmed/17576803
http://dx.doi.org/10.1083/jcb.200701040

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