Cargando…
Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite
Apicomplexan pathogens are obligate intracellular parasites. To enter cells, they must bind with high affinity to host cell receptors and then uncouple these interactions to complete invasion. Merozoites of Plasmodium falciparum, the parasite responsible for the most dangerous form of malaria, invad...
Autores principales: | O'Donnell, Rebecca A., Hackett, Fiona, Howell, Steven A., Treeck, Moritz, Struck, Nicole, Krnajski, Zita, Withers-Martinez, Chrislaine, Gilberger, Tim W., Blackman, Michael J. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064393/ https://www.ncbi.nlm.nih.gov/pubmed/17000879 http://dx.doi.org/10.1083/jcb.200604136 |
Ejemplares similares
-
The Coxsackievirus and Adenovirus Receptor (CAR) Undergoes Ectodomain Shedding and Regulated Intramembrane Proteolysis (RIP)
por: Houri, Nadia, et al.
Publicado: (2013) -
Covalent fragment inhibits intramembrane proteolysis
por: Eden, Angela, et al.
Publicado: (2022) -
Proteolytic Activation of the Essential Parasitophorous Vacuole Cysteine Protease SERA6 Accompanies Malaria Parasite Egress from Its Host Erythrocyte
por: Ruecker, Andrea, et al.
Publicado: (2012) -
Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery
por: Patel, Avnish, et al.
Publicado: (2019) -
A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite
por: Ramaprasad, Abhinay, et al.
Publicado: (2022)