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Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner

FILAMIN B, which encodes a cytoplasmic actin binding protein, is mutated in several skeletal dysplasias. To further investigate how an actin binding protein influences skeletogenesis, we generated mice lacking intact Filamin B. As observed in spondylocarpotarsal synostosis syndrome patients, Filamin...

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Detalles Bibliográficos
Autores principales:	Zheng, Lihua, Baek, Hwa-Jin, Karsenty, Gerard, Justice, Monica J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064428/ https://www.ncbi.nlm.nih.gov/pubmed/17606870 http://dx.doi.org/10.1083/jcb.200703113

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