Cargando…
The Retinoblastoma family member p107 regulates the rate of progenitor commitment to a neuronal fate
The Retinoblastoma protein p107 regulates the neural precursor pool in both the developing and adult brain. As p107-deficient mice exhibit enhanced levels of Hes1, we questioned whether p107 regulates neural precursor self-renewal through the repression of Hes1. p107 represses transcription at the H...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064429/ https://www.ncbi.nlm.nih.gov/pubmed/17591923 http://dx.doi.org/10.1083/jcb.200703176 |