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Heterochromatin is refractory to γ-H2AX modification in yeast and mammals

Double-strand break (DSB) damage in yeast and mammalian cells induces the rapid ATM (ataxia telangiectasia mutated)/ATR (ataxia telangiectasia and Rad3 related)-dependent phosphorylation of histone H2AX (γ-H2AX). In budding yeast, a single endonuclease-induced DSB triggers γ-H2AX modification of 50...

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Detalles Bibliográficos
Autores principales:	Kim, Jung-Ae, Kruhlak, Michael, Dotiwala, Farokh, Nussenzweig, André, Haber, James E.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064441/ https://www.ncbi.nlm.nih.gov/pubmed/17635934 http://dx.doi.org/10.1083/jcb.200612031

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