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Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR

The promyelocytic leukemia (PML) nuclear body (NB) is a dynamic subnuclear compartment that is implicated in tumor suppression, as well as in the transcription, replication, and repair of DNA. PML NB number can change during the cell cycle, increasing in S phase and in response to cellular stress, i...

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Detalles Bibliográficos
Autores principales:	Dellaire, Graham, Ching, Reagan W., Ahmed, Kashif, Jalali, Farid, Tse, Kenneth C.K., Bristow, Robert G., Bazett-Jones, David P.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064496/ https://www.ncbi.nlm.nih.gov/pubmed/17030982 http://dx.doi.org/10.1083/jcb.200604009

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