Cargando…
Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells
Epithelial cells are typically arranged in a honeycomb-like pattern, minimizing their cell–cell contact areas, which suggests that some tension operates for shaping of the cell boundaries. However, the molecular mechanisms that generate such tension remain unknown. We found that Tuba, which is a Cdc...
Autores principales: | Otani, Tetsuhisa, Ichii, Tetsuo, Aono, Shinya, Takeichi, Masatoshi |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064505/ https://www.ncbi.nlm.nih.gov/pubmed/17015620 http://dx.doi.org/10.1083/jcb.200605012 |
Ejemplares similares
-
Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation
por: Qin, Yi, et al.
Publicado: (2010) -
Targeting Rac and Cdc42 GEFs in Metastatic Cancer
por: Maldonado, Maria del Mar, et al.
Publicado: (2020) -
Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG
por: Fukuhara, Tatsuro, et al.
Publicado: (2004) -
Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42–Tuba pathway
por: Juin, Amélie, et al.
Publicado: (2014) -
The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis
por: Rodriguez-Fraticelli, Alejo E., et al.
Publicado: (2010)